Objectives

  1. Implement a development program consisting of i) Design & Engineering, ii) DNA Assembly and Protein Production, and iii) Testing to accumulate a toolbox of synthetic parts, cell lines, and complete signaling circuits.

  2. Develop tools for our signaling toolbox with broad combinatorial potential applicable for different types of signaling cascades.

  3. Develop whole synthetic signaling pathways, which are applicable as screening platforms for new medicines, particularly Cancer and Diabetes.

  4. Develop synthetic signaling cascades, which are transferrable into human cells for the treatment of specific diseases.

  5. Develop human signaling pathways, which are applicable as screening platforms for creating new Flavour, Fragrance and Nutritional ingredients.

  6. Generate technologies and intellectual property that are widely disseminated to the broader European SME and large industry community.

  7. Identify societal perceptions and concerns about synthetic biology in Europe to ensure long-term impact and sustainability of this research.